Korean Journal of Pharmacognosy (생약학회지)
- Volume 27 Issue 1
- /
- Pages.58-64
- /
- 1996
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Biological Activities of Lysimachiae Herba I. -Effects of the Pretreatment of Lysimachiae Herba on the Enzyme Activities in Galactosamine-intoxicated Rats-
금전초(金錢草) 성분의 생리활성 I. -금전초의 추출분획의 전처리가 갈락토사민 중독 흰쥐의 대사효소활성에 미치는 영향-
- Kim, Hoe-Young (College of Pharmacy, Kyungsung University) ;
- Kim, Soon-Shin (College of Pharmacy, Kyungsung University) ;
-
Lee, Chung-Kyu
(College of Pharmacy, Kyungsung University)
;
-
Choi, Jong-Won
(College of Pharmacy, Kyungsung University)
- Published : 1996.03.30
Abstract
Pretreatment of the methanolic extract(250-500mg/kg, p.o., two weeks) of Lysimachiae Herba prevented the elevation of ALT and AST activities in galactosamine(GalN, 400 mg/kg, i.p.) intoxicated rats. Its five fractions, especially the ethyl acetate fraction, also showed significant preventing actions on damaged liver metabolizing enzyme functions by GalN intoxication.