BMB Reports
- 제28권1호
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- Pages.68-71
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- 1995
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- 1976-670X(eISSN)
Synthesis of Peptides by Bovine Gastricsin
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Yoon, Joo-Ok
(Department of Food Science and Technology, College of Engineering, Dongguk University) ;
- Kim, Young-Jun (Department of Food Science and Technology, College of Engineering, Dongguk University)
- 발행 : 1995.01.31
초록
Bovine gastricsin catalyzes peptide synthesis over an optimum range of pH 4~5, resulting in satisfactory yields of methyl esters and p-nitroanilides of benzyloxycarbonyl tetra- to hexa-peptides, provided that hydrophobic amino acid residues form new peptide bonds. The effectiveness of the enzyme also depends on the nature of adjacent amino acid residues. An aspartic proteinase with a characteristic gastricsin specificity pattern would be useful for the synthesis of middle-length peptides.