Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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Effect of Guibitang and Ascorbic Acid on the Regional Brain Catecholamines contents of Heat or Forced Swimming stressed Guinea Pig

귀비탕(歸脾湯)과 Ascorbic Acid가 열(熱) 및 유영(遊泳) Stress Guinea Pig의 뇌(腦) Catecholamine 함량(含量)에 미치는 영향(影響)

  • Ryu Jae-Gyu (Dept. of Oriental Neuropsychiatry Kyung Hee University) ;
  • Whang Wei-Wan (Dept. of Oriental Neuropsychiatry Kyung Hee University)
  • 류재규 (경희대학교 한의과대학 신경정신과교실) ;
  • 황의완 (경희대학교 한의과대학 신경정신과교실)
  • Published : 1995.11.28
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Abstract

This study aimed to compare the anti-stress effect of Guibitang with Ascorbic Acid on the guinea pigs in heat or forced swimming stress. the experimental animals were heated in hot room$(34{\pm}2^{\circ}C)$ for 2 hours in a day during 7 days. Forced swimming stress was loaded by forcing guinea pigs to swim in a oval tub for 2 minutes in a day during 7days. And administered 1.0mg/100g of Ascorbic Acid or 86.0mg/100g of Guibitang extract formonce befor stress. 1. In brain, the contents of norepinephrine in group of the heat of forced swimming stress, in case administered Ascorbic Acid and in case administered Guibitang extract with Ascorbic Acid significantly decreases as compared with these in case administered non Ascoric Acid. 2. In brain, the contents of epinephrine in group of the forced swimming stress, in case administered Guibitang extract with Ascorbic Acid significantly decreases as compared with these in case administered non Ascorbic Acid. 3. In brain, the contents of dopamine in group of the heating stress, in case administered Guibitang extract with Ascorbic Acid significantly decreases as compared with these in case administered non Ascorbic Acid, and these in group of the forced swimming stress in case administered Ascorbic Acid and in case administered Guibitang extract without Ascorbic Acid and in case administered Guibitang extract with Ascorbic Acid significantly decreases as compared with these in case administered non Ascorbic Acid.

Keywords

References

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