The Korean Journal of Physiology
- Volume 29 Issue 2
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- Pages.259-267
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- 1995
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- 0300-4015(pISSN)
Enhanced Expression of Angiotensinogen mRNA in Rat Central and Peripheral Tissues Following Hemorrhage
- Do, Eun-Ju (Department of Physiology, School of Medicine, Kyungpook University) ;
- Yang, Eun-Kyoung (Department of Physiology, School of Medicine, Kyungpook University) ;
- Kim, Kyung-Soon (Department of Physiology, School of Medicine, Kyungpook University) ;
- Kim, Suk-Hee (Department of Physiology, School of Medicine, Kyungpook University) ;
- Park, Yoon-Yub (Department of Physiology, School of Medicine, Kyungpook University) ;
- Ahn, Dong-Kuk (Department of Physiology, School of Medicine, Kyungpook University) ;
- Park, Jae-Sik (Department of Physiology, School of Medicine, Kyungpook University) ;
- Lee, Won-Jung (Department of Physiology, School of Medicine, Kyungpook University)
- Published : 1995.12.30
Abstract
The renin-angiotensin system plays an important role in the regulation of blood pressure and in body fluid homeostasis. There is increasing evidence for generation of endogenous angiotensin II in many organs and for its role in paracrine functions. Studies were designed to investigate whether hemorrhage produces rapid changes in the gene expression of angiotensinogen in peripheral and brain tissues. Wistar rats received saline drinking water for 7 days, were bled at a rate of