Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Kimura's Disease - Clinical Characteristics and Treatment Outcomes -

기무라병의 임상특성과 치료성적

  • Hong Soon-Gi (Department of Surgery, Yonsei University College of Medicine) ;
  • Choi Jin-Sub (Department of Surgery, Yonsei University College of Medicine) ;
  • Park Cheong-Soo (Department of Surgery, Yonsei University College of Medicine)
  • 홍순기 (연세대학교 의과대학 외과학교실) ;
  • 최진섭 (연세대학교 의과대학 외과학교실) ;
  • 박정수 (연세대학교 의과대학 외과학교실)
  • Published : 1994.06.01
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Abstract

The clinical features and treatment outcomes of 20 patients with Kimura's disease treated from 1981 to 1993 were analyzed to determine proper therapeutic modalities. The mean age was 36.3 yrs old (range l4-53yrs) and the male to female ratio was 1.5:1 (male:female=12:8). Among 20 patients, 13 had multiple lesions and the remaining 7 had single lesion. Almost all lesions were found in the head and neck area(41 lesions) and only 7 in the other sites. The initial treatment modalities were excision, excision with immunotherapy, radiotherapy with immunotherapy, or immunotherapy(steroid, azathioprine). Among 17 patients who could be followed up, a recurrent or persistent disease was found in 13 patients. The retreatment modalities for patients with recurrent lesions were excision, excision with immunotherapy, or immunotherapy. The retreatment outcomes were also disappointing. The proper therapeutic modality of the Kimura's disease is not established yet, but the radiotherapy after excision or immunotherapy seems to be more effective than others.

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