Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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A Case of Idiopathic Hypereosinophilic Syndrome Associated with Pulmonary Infiltration

폐 침윤을 동반한 특발성 과호산구 증후군 1례

  • Rhu, Hon-Mo (Department of Internal Medicine College of Medicine, Yeungnam University) ;
  • Kweon, Young-Soo (Department of Internal Medicine College of Medicine, Yeungnam University) ;
  • Chung, Jin-Hong (Department of Internal Medicine College of Medicine, Yeungnam University) ;
  • Lee, Kwan-Ho (Department of Internal Medicine College of Medicine, Yeungnam University) ;
  • Lee, Hyun-Woo (Department of Internal Medicine College of Medicine, Yeungnam University) ;
  • Kim, Dong-Sug (Department of Pathology College of Medicine, Yeungnam University) ;
  • Lee, Sam-Beom (DaeNam Hospital)
  • 류헌모 (영남대학교 의과대학 내과학교실) ;
  • 권영수 (영남대학교 의과대학 내과학교실) ;
  • 정진홍 (영남대학교 의과대학 내과학교실) ;
  • 이관호 (영남대학교 의과대학 내과학교실) ;
  • 이현우 (영남대학교 의과대학 내과학교실) ;
  • 김동석 (영남대학교 의과대학 병리학교실) ;
  • 이삼범 (청도대남병원)
  • Published : 1994.12.30
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Abstract

The idiopathic hypereosinophilic syndrome consists of peripheral blood eosinophilia of $1500/mm^3$ or more without a known cause, plus signs and symptoms of organ eosinophilia. The prognosis of HES without treatment is poor. However, about one third of the patients with this syndrome may respond to corticosteroid thrapy. Morever, the majority of the remainder may have a favorable response to hydroxyurea. We present here a case of hypereosinophilic syndrome without any identifiable causes, involving bone marrow, liver, lungs and cervical lymph node. We tried corticosteroid as a treatment but it showed no response. However the hydroxyurea showed good response.

저자들은 말초 혈액에서 현저한 호산구 증가를 보이면서 간, 임파선, 골수 및 폐에 호산구 침윤을 보여 hydroxyurea로 치료한 특발성 과호산구 증후군 1례를 경험하였기에 문헌고찰과 함께 보고하는바이다.

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