한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)
- 제9권1호
- /
- Pages.15-21
- /
- 1994
- /
- 1229-1153(pISSN)
- /
- 2465-9223(eISSN)
UV-A 조사에 의한 Phenothiazines의 돌연변이원성 비교 연구
Comparative Study on the Mutagenic Activity of Phenothiazines by UV-A Irradiations
초록
The mutagenic activity of four phenothiazine derivatives such as chlorpromazine, perphenazine, trifluoperazine and thioridazine in conjunction with UV-A irradiation or not based on the Ames plate incorporation test in the presence and absence of liver microsomal enzyme(S9 fraction). None of these compounds and their photo-excited were detected as mutagen in the Salmonella microsome assay with TA 98 and TA 100.