Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Production of Itaconic Acid at Various Bioreactors

다양한 생물반응기에서 이타콘산의 생산

  • 박승원 (수원대학교 유전공학과) ;
  • 김승옥 (수원대학교 유전공학과) ;
  • 이진석 (한국에너지기술연구소)
  • Published : 1994.06.01
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Abstract

A suitable culture method and bioreactor type for itaconic acid production were chosen by comparing the maximal concentration of itaconic acid produced in various systems. In batch culture, the maximal concentration of itaconic acid produced in a bubble column reactor was about 5% greater than that produced in stirred-tank or external-loop airlift reactor. These results were thought to be due to lower shear force and higher mass transfer efficiency in a bubble column reactor in comparison with other reactors. Moreover, the fed-batch mode in a bubble column was found to be a suitable one, producing about 25% higher concentration of itaconic acid compared to batch mode.

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References

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