Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Antihyperglycemic Constituent of Aralia elata Root Bark(II) -Isolation and Action of the Constituents-

두릅나무 근피의 혈당강하 성분에 관한 연구(II) -유효성분의 분리 및 작용-

  • Kim, Ok-Kyung (College of Natural Sciences, Seoul Woman's University) ;
  • Lee, Eun-Bang (Natural Products Research Institute, Seoul National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University)
  • 김옥경 (서울여자대학교 자연과학대학) ;
  • 이은방 (서울대학교 천연물과학연구소) ;
  • 강삼식 (서울대학교 천연물과학연구소)
  • Published : 1993.09.30
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Abstract

An antihyperglycemic compound in a model of alloxan induced diabetic rats was isolated from the root bark of Aralia elata. The compound identified to be oleanolic acid $28-O-{\beta}-_D-glucopyranoside$ was active at a dose of 100 mg/kg p.o. in the rats. It also has increased the contents of liver glycogen which were lowered by injection of alloxan in the rats.

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