Journal of Yeungnam Medical Science
- 제9권1호
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- Pages.44-53
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- 1992
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- 2799-8010(eISSN)
Kawasaki병에 있어 아스피린 단독 투여시와 정맥내 감마 글로불린 병용시에 치료효과에 대한 연구
A Comparative Study of Therapeutic Effect of Aspirin Alone and Intravenous Gammaglobulin Plus Aspirin in Kawasaki Disease
- Hwang, Young-Hee (Department of Pediatrics College of Medicine, Yeungnam University) ;
- Jun, Jin-Gon (Department of Pediatrics College of Medicine, Yeungnam University) ;
- Kim, Chun-Dong (Department of Pediatrics Soonchunhyang Hospital)
- 발행 : 1992.06.30
초록
1985년 9월부터 1990년 8월까지 만 5년간 영남대학교 의과대학부속병원 소아과에 입원하여 가와사끼병으로 진단된 환아를 대상으로 아스피린 단독 치료한 A군과 아스피린과 정맥내 면역글로불린을 병용 치료한 B군으로 나누어 발열기간, 혈액검사소견 및 심초음파 검사소견을 비교 분석하여 다음과 같은 결론을 얻었다. 1) 발열기간은 A군과 B군에서 치료 시작전까지의 기간에서는 별 차이가 없었으나, 치료 시작후 발열기간은 B군이
We compared the efficacy of each modality of treatment group in reducing the frequency of coronary artery abnormalities and changes of clinical courses in children with kawasaki disease in the children of 81 cases who were admitted in pediatric department of Yeungnam University Hospital from September 1985 to August 1990, Group A(37 cases)-aspirin alone, Group B(44 cases)-intravenous gammaglobulin(400mmg/kg/day) for 5 consecutive days, plus aspirin. We studied the frequency of echocardiographic abnormalities, the duration of fever, and changes in the total white blood cell counts, platelet counts, ESR and CRP value at 1, 2 and 3 weeks of the illness and compared the results between the two groups. The results were as follows, 1) There as no significant intergroup difference in age and sex ratio. 2) The duration of the febrile period after the initiation of the therapy was significant shorter in group B(