Applied Biological Chemistry
- Volume 35 Issue 3
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- Pages.157-164
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- 1992
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- 2468-0834(pISSN)
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- 2468-0842(eISSN)
Production of NAD from adenine and nicotinamide by Saccharomyces sake KBA No.6
Saccharomyces sake KBA No. 6에 의한 adenine과 nicotinamide로부터 nicotinamide adenine dinucleotide(NAD)의 생산
- Choi, In-Girl (Department of Agricultural Chemistry, Korea University) ;
- Hwang, Ki-Chul (Department of Agricultural Chemistry, Korea University) ;
- Bang, Won-Gi (Department of Agricultural Chemistry, Korea University)
- Published : 1992.06.30
Abstract
In order to produce nicotinamide adenine dinucleotide (NAD) which is a pyridine nucleotide coenzyme, Saccharomyces sake KBA No. 6 having high NAD content was selected from 12 strains of yeast and various factors affecting the production of NAD were investigated. For NAD production, 4% of glucose was effective as a carbon source and 2% of bactopeptone was the best nitrogen source. The optimum pH and temperature was 5.0 and
미생물을 이용하여 pyridine계 보효소인 NAD를 생산하기 위하여, 12종의 효모로부터 NAD 함량이 높은 Saccharomyces sake KBA No. 6을 선별하였으며, NAD 생산에 미치는 여러 가지 효과를 검토하였다. NAD 생산에 있어서 탄소원으로는 4% glucose, 질소원으로는 2% bactopeptone이 가장 좋았으며 최적 PM와 온도는 각각 5.0과