YAKHAK HOEJI (약학회지)
- Volume 36 Issue 3
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- Pages.255-258
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- 1992
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Characterization of Tetracycline Resistant Plasmid in Staphylococcus aureus by Restriction Enzyme Mapping
황색포도상구균에서 테트라사이클린 내성을 나타내는 플라스미드의 동정
- Kim, Ki-Hyun (College of Pharmacy, Kyungsung University) ;
- Kim, Jong-Myung (College of Pharmacy, Kyungsung University) ;
- Moon, Kyung-Ho (College of Pharmacy, Kyungsung University)
- Published : 1992.06.29
Abstract
The clinical isolate Staphylococcus aureus SA8 was resistant to tetracycline(Tc) and harboured a plasmid pKH1(24.82 kb). pKH1 was shown by curing and by transformation to specify resistance to Tc. The cleavage map of a pKH1 was determined by restricction enzyme mapping techniques. Cleavage map is given for BglII, EcoRI, HpaII, PvuII and SalI. Restriction endonuclease BamHI, BglI, BstEII, HpaI, PstI, and XhoI have no sites on this plasmid. HaeIII, XbaI, and HindIII have 5, 6, 14 sites, respectively.
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