KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Extraction of Indole Alkaloids from Catharanthus roseus by Using Supercritical Carbon Dioxide with Ethanol

초임계 이산화탄소와 에탄올을 이용한 일일초로부터 인들 알칼로이드의 추출에 관한 연구

  • 송규민 (한국과학기술원 화학공학과 생물공정연구센터) ;
  • 박상우 (한국과학기술원 화학공학과 생물공정연구센터 한국과학기술원 화학공학과 생물공정연구센터 한국과학기술원 화학공학과 생물공정연구센터 한국과학기술연구소 유전공학센터 한국과학기술연구소 유전공학센터)
  • Published : 1991.12.01
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Abstract

The extraction of indole alkaloids from Catharanthus roseus using the supercritital carbon dioxide with ethanol was performed in various temperature and pressure conditions. The contents of vindoline in the extracts were determined by HPLC. In this study, the flow rate of cosolvent ehtanol was 20.4$\mu$l/min, about 3 wt.% of flow rate of supercritical carbon dioxide. However the effect of ethanol on the yield of extracted vindoline was not significant.

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