YAKHAK HOEJI (약학회지)
- Volume 35 Issue 1
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- Pages.11-14
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- 1991
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Mechanism of Platelet Activation Induced by Cyclic Peptide, Ro09-0198
Cyclic Peptide, Ro09-0198의 혈소판활성화에 대한 작용기전
Abstract
Ro09-0198, a cyclic peptide isolated from culture filtrates of Streptoverticillium griseove-rticillatum, induced platelet aggregation and serotonin release simultaneously. LDH release was not observed. Addition of peptide to rat platelet, loaded with
Keywords
- Ro09-0198;
- platelet aggregation;
- serotonin release;
- quin-2;
- $Ca^{2+}$;
- phosphatidyletanolamine;
- liposome