Cyclodextrin as a Biomimetic Model Enzyme- the Catalysis of Aspirin Hydrolysis Included by Cyclodextrins

생체효소 유사물질로서의 시클로덱스트린의 작용- 시클로덱스트린으로 포접된 아스피린의 가수분해 촉매작용-

The molecular nature of aspirin hydrolysis was studied using cyclodextrin as a biomimetic model for esterase. Cyclodextrin was selected for this purpose because it meets the necessary requirements for the hydrolysis study, Dissociation constants and catalytic rates were obtained under alkaline conditions by the kinetic method.