Korean Journal of Veterinary Research (대한수의학회지)
- Volume 30 Issue 4
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- Pages.447-457
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- 1990
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
Histopathological studies on the influence of mast cell in the growth of rat mammary carcinoma 1. Distribution of mast cell on the development of DMBA-induced mammary carcinoma
Rat mammary carcinoma의 발육(發育)에 있어서 비만세포(肥滿細胞)의 영향(影響)에 관한 병리조직학적(病理組織學的) 연구(硏究) 1. DMBA 투여(投與)에 의한 발암(發癌)과 비만세포(肥滿細胞)의 분포상황(分布狀況)
- Kim, Tae-hwan (Laboratory of Experimental Animal, Korea Cancer Center Hospital, Korea Atomic Energy Research Institute) ;
- Lee, Cha-soo (College of Veterinary Medicine, Kyungpook National University)
- Received : 1990.08.21
- Published : 1990.10.31
Abstract
In order to observe the distribution of mast cell on the stages of the mammary carcinogenesis, the numerical changes of mast cells in the mammary tumor development in rats treated with DMBA and compound 48/80 have been investigated by the light microscope. The results observed were summarized as follows: The appearance of tumor were not observed during the whole experimental period in the rats of the control group received injection of sterile saline, but tumors appeared in 100% of the animals, the tumor induction time that represented the number of days elapsing between the 3rd DMBA administration until a first tumor became