Applied Biological Chemistry
- 제33권2호
- /
- Pages.169-173
- /
- 1990
- /
- 2468-0834(pISSN)
- /
- 2468-0842(eISSN)
자몽종자 추출물(DF-100)이 Penicillium islandicum생육 및 독소 성분 skyrin생합성에 미치는 저해효과
Inhibitory effects of grapefruit seed extract(DF-100) on growth and toxin production of Penicillium islandicum
-
Cho, Sung-Wan
(Dept of Food Technology, Gyeongsang National University)
;
- Seo, Il-Won (ABCON CHEMIE Co., Ltd.) ;
- Choi, Jong-Duck (Dept of Food Technology, National Tongyong Fisheries Technical College) ;
- Joo, In-Saeng (Dept of Food Technology, Gyeongsang National University)
- 발행 : 1990.06.30
초록
곡류 등에 오염되어 황색 독소성분인 skyrin을 생합성하는 Penicillium islandicum 배지에 grapefruit 종자로부터 추출한 천연유기 복합물인 DF-100을 처리하여 곰팡이 생육 및 skyrin 생성을 저해하는 효과를 볼 수 있었다. DF-100 500ppm 농도로 Penicillium islandicum의 생육을 91% 저해하였고 750ppm 농도에서 곰팡이 생육을 완전히 저해하였으며 500ppm농도로 skyrin생성을 완전히 저해하였다. skyrin 생합성경로를 고려할 때 DF-100은 낮은 농도에서 emodinanthrone으로부터 emodin을 거쳐 skyrin으로 전환되는 효소 반응계와 skyrinanthrone으로 진행하는 반응단계를 저해하는 것으로 밝혀 졌다.
The anthraquionone mycotoxin, skyrin, is produced by Penicillium islandicum. DF-100 which was extracted from grapfruit seed extract and is a natural organic complex inhibited the biosynthesis of skyrin by Penicillium islandicum. This study was carried out to determine the potential of DF-100 to support Penicillium islandicum and skyrin production. DF-100 inhibited the growth of the fungus at 750ppm or less and caused complete inhibition of skyrin production at 500ppm or less. DF-100 appears to block the incorporation of emodinathrone into skyrin and an enzymatic step in the skyrin biosynthetic pathway which lies before skyrinanthrone.