Journal of Pharmaceutical Investigation
- Volume 20 Issue 3
- /
- Pages.135-144
- /
- 1990
- /
- 2093-5552(pISSN)
- /
- 2093-6214(eISSN)
The Solubilization Behavior of DOPE-Immunoliposomes with Immunoglobulin G(IgG) by Added Bile Salts
Immunoglobulin G(IgG)를 함유한 DOPE 리포솜의 제조와 담즙산염에 의한 용해 특성
- Lee, Eun-Ok (Department of Chemical Engineering and Bioprocess ERC, KAIST) ;
- Kim, Jin-Gu (Department of Chemical Engineering and Bioprocess ERC, KAIST) ;
- Kim, Jong-Duk (Department of Chemical Engineering and Bioprocess ERC, KAIST)
- Published : 1990.09.20
Abstract
The effects of bile salts (BS) on the stability of dioleoylphosphatidylethanolamine (DOPE) liposomes were investigated, observing apparent absorbance of vacant liposomes and calcein release from entrapped liposomes. Unilamellar liposomes were prepared by using a small quantity of palmitoly-immunoglobulin G(IgG) (