Journal of Pharmaceutical Investigation
- Volume 20 Issue 4
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- Pages.205-208
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- 1990
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Effect of Azone on Penetration of Antiviral Agents through Hairless Mouse Skin
무모(無毛) 마우스의 피부를 통한 항바이러스제의 투과와 Azone의 영향
- Choi, Seung-Ho (College of Pharmacy, University, of Utah) ;
- Kim, Johng-Kap (College of Pharmacy, Chung-Ang University)
- Published : 1990.12.20
Abstract
1-Dodecylazacycloheptan-2-one (Azone) is a new agent that enhances the percutaneous penetration of a number of different chemicals. BVDU and FEAU were evaluated for their potential efficacy in the treatment of cutaneous herpes simplex virus infections by in vitro studies through hairless mouse skin. This study demonstrates the value of penetration enhancing agent (Azone) and the need for a predictable evaluations in the development of topical antiviral agents.
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