YAKHAK HOEJI (약학회지)
- Volume 34 Issue 1
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- Pages.40-46
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- 1990
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Pharmacokinetics of Praziquantel in Rabbits
가토에서의 Praziquantel의 체내 동태
- Lee, Mi-Jeong (College of Pharmacy, Seoul National University) ;
- Shim, Chang-Koo (College of Pharmacy, Seoul National University) ;
- Lee, Min-Hwa (College of Pharmacy, Seoul National University) ;
- Kim, Shin-Keun (College of Pharmacy, Seoul National University)
- Published : 1990.02.28
Abstract
Pharmacokinetic studies on praziquantel in rabbits were performed in this paper. The pharmacologically active parent drug was separated from the pharmacologically inactive metabolites by HPLC method. The pharmacokinetic parameters of parent drug were obtained. In vitro partition to blood cells of praziquantel was measured. The mean value (n = 3) of partition to blood cells was 44% at concentrations between