Archives of Pharmacal Research
- 제12권1호
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- Pages.5-7
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- 1989
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis of Substituted Arylazothioxanthones as Potential Schistosomicidal Agents
- El-Kerdawy, M.M. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
- El-Emam, A.A. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
- El-Subbagh, H.I. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
- Abushanab, E. (Department of Medicinal Chemistry, College of Pharmacy)
- 발행 : 1989.03.01
초록
A series of 1-chloro-4-methyl-6-arylazo-9H-thioxanthen-9-ones were synthesized and schistosomicidal activity evaluated. It was found that, 1-chloro-4-methyl-6-(2-hydroxy-1-naphthylazo)-9H-thioxanthen-9-one possessed a promising activity against Schisto-soma mansoni in mice.