약학회지 (YAKHAK HOEJI)
- 제32권5호
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- Pages.328-333
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- 1988
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
금은화(Lonicerae Flos)의 Ethyl Acetate 분획이 돌연변이원성에 미치는 영향
Effects of Lonicerae Flos' Ethyl Acetate Fraction on Mutagenicity
- Chung, Kyu-Charn (College of Pharmacy, Yeungnam University) ;
- Kwon, Dong-Yeul (College of Pharmacy, Yeungnam University) ;
- Baek, Suk-Hwan (College of Pharmacy, Yeungnam University) ;
- Kim, Sung-Hwan (College of Pharmacy, Yeungnam University) ;
- Chang, Hyeun-Wook (College of Pharmacy, Yeungnam University)
- 발행 : 1988.08.29
초록
Based on the following tests with fractions extracted from organic solvents such as benzene, chloroform, ethyl acetate and methanol, this study is to analyse the antimutagenicity of Lonicerae Flos. When carrying out Ames test with Salmonella typhimurium strain, it seemed that there was stronger antimutagenicity in TA 100 treated by MNNG than did one in TA 98 by NPD, and that there was stronger antimutagenicity through base pair exchange than one through frame shift. In the umu test, each fraction tended to inhibit the activity of
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