Effecrs of Leonurus sibiricus extract on experimentally induced liver damage and alloxan diabetes in Rabbits

익모초녹즙(益母草綠汁)이 가토(家兎)의 간장장애(肝臟障碍) 및 고혈당(高血糖)에 미치는 영향(影響)

  • Sheo, Hwa-Joong (Dept. of Food and Nutrition, College of Industry, Chosun University) ;
  • Kook, Hyun-Sook (Dept. of Food and Nutrition, College of Industry, Chosun University) ;
  • Lee, Myung-Yul (Dept. of Food and Nutrition, College of Industry, Chosun University)
  • 서화중 (조선대학교 산업대학 식품영양학과) ;
  • 국현숙 (조선대학교 산업대학 식품영양학과) ;
  • 이명열 (조선대학교 산업대학 식품영양학과)
  • Published : 1987.02.28

Abstract

These studies were conducted to investigate the effects of Leonurus sibiricus extract (L.S.E.) on experimentally $CCl_4-induced$ liver damage and alloxan-induced diabetes in rabbits; Leonurus sibiricus juice (L.S.J.) showed the most rapid recuperation of liver function among samples compared to the control group in $CCl_4-intoxicated$ rabbits. SGPT activity stowed an apparant decreasing effect in 4 days, and the blood level of total cholesterol and total bilirubin in 6 days, and not in alkaline phosphatase level. L.S.J. exhibited more excellent hypoglycemic effect in alloxan-induced diabetes of rabbits, that is, significant to the control group after 2 days and adjacent to the normal level on 8th day. And SGPT activity and total cholesterol level were gradually decreased and showed markedly decreasing effect after 4 days.

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