The Journal of the Korean Society for Microbiology (대한미생물학회지)

The Korea Society for Microbiology (대한미생물학회)
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Antibacterial Activity of Soluble Extracts of Gardenia jasminoides against Mycobacteria Other Than Tubercle Bacilli

치자(梔子) 수용성 추출액의 결핵균 외의 기타 Mycobacteria에 대한 항균작용

  • Choi, Chul-Soon (Department of Microbiology, Chung-Ang University, College of Medicine) ;
  • Shin, Seung-Shik (Department of Microbiology, Chung-Ang University, College of Medicine) ;
  • Chung, Sang-In (Department of Microbiology, Chung-Ang University, College of Medicine) ;
  • Yang, Yong-Tae (Department of Microbiology, Chung-Ang University, College of Medicine)
  • 최철순 (중앙대학교 의과대학 미생물학교실) ;
  • 신승식 (중앙대학교 의과대학 미생물학교실) ;
  • 정상인 (중앙대학교 의과대학 미생물학교실) ;
  • 양용태 (중앙대학교 의과대학 미생물학교실)
  • Published : 1986.03.31
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Abstract

An attempt was made to verify the antibacterial activities of the soluble extracts of Gardenia jasminoides(SEGJ) against mycobacteria other than tubercle bacilli (MOTT); M. kansasii, M. scrofulaceum, M. simiae, M. szulgai, M.xenopi, M. avium-intracellulare complex, M. gordonae and M. flarescens. In addition, the effect of the SEGJ on the yellow pigmentation and violet pigmentation (crocin reaction) of the colonies of the MOTT grown on7H10-crocin agar plates was observed. The SEGJ gave a growth stimulatory activity against most species of mycobacteria except for M. szulgai at low concentration of the SEGJ in terms of crocin pigment OD=0.02 or less, but exerted an inhibitory activity at high concentration of OD=0.04 or more. The growth-inhibitory activity of the SEGJ was dose-dependent but the yellow pigmentation of the scotochromogens was not affected by the dose of the SEGJ that was growth-inhibitory. Crocin positive reaction was observed only with M. kansasii.

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