The Korean Journal of Pharmacology (대한약리학회지)
- Volume 22 Issue 2
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- Pages.88-95
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- 1986
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- 0377-9459(pISSN)
Reevaluation of the Effect of Phenobarbital on the Response to Pain in Rat
백서에서 동통에 미치는 Phenobarbital 효과의 재평가
- So, Byoung-Gyoum (Department of Pharmacology, College of Medicine, Chonbuk National University) ;
-
Kim, Kee-Won
(Department of Pharmacology, College of Medicine, Chonbuk National University) ;
- Ko, Myoung-Kyu (Department of Pharmacology, College of Medicine, Chonbuk National University) ;
- Yang, Won-Mo (Department of Pharmacology, College of Medicine, Chonbuk National University) ;
- Cho, Kyu-Park (Department of Pharmacology, College of Medicine, Chonbuk National University)
- 소병겸 (전북대학교 의과대학 약리학교실) ;
-
김기원
(전북대학교 의과대학 약리학교실) ;
- 고명규 (전북대학교 의과대학 약리학교실) ;
- 양원모 (전북대학교 의과대학 약리학교실) ;
- 조규박 (전북대학교 의과대학 약리학교실)
- Published : 1986.12.30
Abstract
Clinically, subhypnotic doses of barbiturates have been known to elicit hyperalgesia. In this experiment, effect of acute or chronic phenobarital treatment on the response to pain in rat was reevaluated by hot-plate method. To elucidate its mechanism, changes of
백서에서 열판법을 이용하여 과민동통을 일으키는 약물로 알려진 phenobarbital의 동통에 대한 효과를 재검토하고 그 기전을 알고저 phenobarbital 단기 또는 장기처리에 의한 뇌내