Radiation Oncology Journal

The Korean Society for Radiation Oncology (대한방사선종양학회)
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Radiosensitivity and Dobe-Survival Characteristics of Crypt Cells of Mouse Jejunum

마우스공장 소낭선세포의 방사선 감수성에 관한 실험적 연구

  • Huh, Seung-Jae (Department of Radiology, College of Medicine, Soonchunhyang University) ;
  • Park, Charn-Il (Department of Therapeutic Radiology, College of Medicine, Seoul National University)
  • 허승재 (순천향대학 의학부 방사선과학교실) ;
  • 박찬일 (서울대학교 의과대학 치료방사선과학교실)
  • Published : 1985.06.01
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Abstract

To determine the radiosensitivity and dose-survival characteristics of jejunal crypt cells, experimental study was done using total 40 mice. Single irradiation of 1,000 rad to 1,600rad was delivered to whole bodies of mice, using a cesium 137 animal irradiator. The number of regenerating crypts per jejunal circumference was counted, by using a jejunal crypt cell assay technique, and dose response curve was measured. The average number of jejunal crypt Per circumference in control group was $140\pm10$. Mean lethal dose$(D_0)$ of moose jejunal crypt cell was 135rad.

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