Urokinase Therapy in Cerebral Thrombosis

뇌혈전에 대한 Urokinase요법의 임상효과

Since opening of the Yeungnam University Hospital in June 1983 till end of 1984, total 30 cases of cerebral thrombosis were analysed clinically. Among the 30, 17 cases were given Urokinase from 60,000 to 240,000 units daily for 2-46 days. The interval from the onset to the inititiation of therapy varied from 1 hour to 17 days. Ten cases showed marked recovery and 6 cases moderate improvement. One case, in which only 120,000 units daily were administered, showed stationary course. The interval of the Urokinase untreated 13 cases was from 3 days to 18 months. Six cases were stationary, whereas 7 cases showed mild improvement. Age, sex, past history, associated diseases, and the laboratory findings are shown in the tables. Conclusion is that the earlier the therapy started, the higher the dosage used, the better of the results is obtained.

1983년 6월부터 1984년 말까지 영대병원 신경과에 입원하였던 뇌혈전 환자 총 30명 중 Urokinase를 사용한 17례와 안 한 환자 13례의 치료 효과를 분석 검토하였다. 10례에서 회복하였고 6례에서 호전하였으며 1례는 효과가 없었다. 이러한 성적은 국내외 타 병원에 비해서 성적이 우수하다고 볼 수 있으며 그 이유는 발병 후 조속한 시일내에 고단위를 썼기 때문이라고 추측된다.