Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Studies on Stability and Quantitation of a Mixed Preparation of Lactic Acid Bacteria

유산균(乳酸菌) 혼합(混合) 제제(製劑)의 안정성(安定性) 및 분리(分離) 정량(定量)에 관한 연구

  • Kim, Jung-Woo (Dept. of Microbial Chemistry, College of Pharmacy, Seoul National University) ;
  • Choi, Eung-Chil (Dept. of Microbial Chemistry, College of Pharmacy, Seoul National University) ;
  • Kim, Byong-Kak (Dept. of Microbial Chemistry, College of Pharmacy, Seoul National University)
  • 김정우 (서울대학교 약학대학 미생물약품화학교실) ;
  • 최응칠 (서울대학교 약학대학 미생물약품화학교실) ;
  • 김병각 (서울대학교 약학대학 미생물약품화학교실)
  • Published : 1984.03.30
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Abstract

To examine stability and a separate quantitative method of a mixed preparation of lactic acid bacteria, a capsule containing Lactobacillus acidophilus, Lactobacillus bulgaricus and Streptococcus thermophilus was suspended and diluted in sterile water. After the diluted suspension was spread on three media of tryptone glucose extract agar, MRS agar and MRS-sucrose agar, their colonies appeared and were counted. The viable counts exceeded the minimum number of the three bacteria and showed that the mixed preparation was stable at least for 18 months. The results also showed that a separate quantitation of viable cells of the each strain was feasible.

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