Archives of Pharmacal Research
- Volume 5 Issue 1
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- Pages.7-12
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- 1982
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Isolation of ginsenosides Rb1, Rb2, Rc Rd, Re, Rf and Rg1 from cinseng root by high performance liquid chromatography
- Paik, Nam-Ho (College of Pharmacy, Seoul National University) ;
- Park, Man-Ki (College of Pharmacy, Seoul National University) ;
- Choi, Kang-Ju (Korea Ginseng and Tobacco Research Institute) ;
- Cho, Yung-Hyun (College of Pharmacy, Seoul National University)
- Published : 1982.06.01
Abstract
Ginsenosides Rb1, Rb2, Rc, Rd, Re, Rf and Rg1 were effectively isolated from ginseng root by preparative liquid chromatography (LC) on two PrepPAK-500/c18 cartridges in series and semipreparative LC on a .mu. Bondapak cabohydrate analysis column, a .mu.Bondapak C18 column or a .mu. Porasil column. The identities of the isolated ginsenosides were confirmed by analytical high-performance liquid chromatography (HPLC) and infrared spectrophotometry. By this method large scale isolation of pure ginsenosides was efficiently accomplished.