Studies on the Efficacy of Combined Preparation of Crude Drugs (X) -Effects of "Oyo-Tang" on the CNS and Ileum of Mice and Guinea-pigs-

생약복합제제의 약효연구(제10보) -오요탕이 중추신경계 및 장관에 미치는 영향-

In order to investigate the pharmacological action of combined preparation of crude drugs, 'Oyo-Tang' were studied. 'Oyo-Tang' consist of Glycyrrhizae Radix, Ephedrae Herba, Armenicae Semen, Platycodi Radix and Nepetae Herba. They have widely been prescribed in Oriental Medicine for controlling of cough, asthma, nasal abstraction, pharygeal pain and hoarseness. Experimental studies were implemented on analgesic, sedativc, anticonvulsive and ileum relaxing actions. The results of the studies were as follows; Significant anticonvulsive action was recognized by fraction IIII. Sedative and analgesic actions were noted by fraction I and III. Relaxing action was shown on the extracted ileum in mice, antagonistic actions were seen on $BaCl_2-induced$ contraction of the ileum of mice and Histamine-induced contraction of the ileum of guinea-pigs that the relaxing effect of the intestinal smooth muscle was recognized.