Studies on the Efficacy of Combined Preparations of Crude Drugs (IV) -Effect of ‘Whangryonhaedok-Tang’ on the Central Nervous System-

생약복합제(生藥複合劑)의 약효연구(藥效硏究) 제4보(第4報) -황연해독탕(黃連解毒湯)의 중추신경계(中樞神經系) 작용(作用)에 대(對)하여-

In order to investigate the pharmacological action of combined preparation of crude drugs, 'Whangryonhaedok-Tang' were studied. Pharmacological studies of the water extract, methanol insoluble fraction and methanol soluble fraction obtained from 'Whangryonhaedok-Tang' were conducted. The results of this investigation were summarized as follows; Central convulsions induced by strychnine, picrotoxine and caffeine were depressed in mice. Analgesic effect was observed in mice and rats. Antipyretic effect was observed in rats and rabbits. Sedative effect was observed.