The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Functional Evaluation of TSH Secretory Reserve Capacity in Hypothalamopituitary Disorders

시상하부-뇌하수체 질환에 있어서 뇌하수체의 TSH 분비능에 관한 연구

  • Kim, Sun-Yong (Department of Radiology & Nuclear Medicine, College of Medicine, Yonsei University) ;
  • Choi, Kyoo-Ok (Department of Radiology & Nuclear Medicine, College of Medicine, Yonsei University) ;
  • Park, Chang-Yun (Department of Radiology & Nuclear Medicine, College of Medicine, Yonsei University) ;
  • Huh, Kab-Bum (Department of Internal Medicine, College of Medicine, Yonsei University) ;
  • Ryu, Kyung-Ja (Department of Pharmacology, College of Medicine, Yonsei University)
  • 김선용 (연세대학교 의과대학 방사선과학교실) ;
  • 최규옥 (연세대학교 의과대학 방사선과학교실) ;
  • 박창윤 (연세대학교 의과대학 방사선과학교실) ;
  • 허갑범 (연세대학교 의과대학 내과학교실) ;
  • 유경자 (연세대학교 의과대학 약리학교실)
  • Published : 1979.11.20
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Abstract

The TRH stimulation test was known as a highly diagnostic method in hypothalamopituitary disorders. To evaluate the location and the extension of the lesion, we estimated TSH response to TRH test in 27 patients. Correlation between volume of sella and TSH response was also studied. The results obtained were as follows: 1. In Sheehan's syndrome, TSH response after TRH test were not observed in all of 12 patients. 2. All 2 acromegaly patients showed normal TSH response. 3. In 4 cases of chromophobe adenoma, 2 cases showed no TSH response. In 2 responded cases, one patient whose tumor mass extended to suprasella region was hypothyroid state. 4. In craniopharyingioma 3 cases, the tumor which extended to intrasella showed hypothyroid and no TSH response. 5. Correlation between volume of sella and TSH response were valuable in 2 cases, but no diagnostic significance. 6. In diabetes inspidus, TSH response were all absent. 7. In primary amenorrhea, TSH response observed in 1 case, which conformed with isolated FSH deficiency.

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