Journal of Pharmaceutical Investigation
- Volume 9 Issue 4
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- Pages.8-12
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- 1979
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
A Study of the Effects of the Root Components of Angelica koreana Max. on Voluntary Activity in Mice
강활(羌活) 성분(成分)이 Mouse 자발운동(自發運動)에 미치는 영향(影響)
- Shin, Hyun-Shick (College of Pharmacology, Chung Buk National Uni.) ;
- Kim, Hak-Seang (College of Pharmacology, Chung Buk National Uni.) ;
- Chi, Hyung-Joon (Natural Products Research Institute, Seoul National Uni.) ;
- Kim, Jae-Wan (College of Pharmacy, Duk Sung Women's College)
- Published : 1979.12.20
Abstract
A study on the effects of the root components of Angelica koreana Max. on voluntary activity in mice has confirmed that: 1. MeOH soluble Ex., MeOH insoluble Ex., oxypucedanine and isoimperatorin were antagonized against the voluntary activity in mice pretreated with a dose of C.N.B. 30mg/kg. 2. MeOH insoluble Ex. showed higher depressant effect than MeOH soluble Ex.. 3. the depressant activity of oxypucedanine was significantly more effective than that of isoimperatorin.
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