YAKHAK HOEJI (약학회지)
- Volume 16 Issue 4
- /
- Pages.176-179
- /
- 1972
- /
- 0377-9556(pISSN)
- /
- 2383-9457(eISSN)
The effect of several cholanic acid derivatives on bile secretion
담즙산류가 담즙배출에 미치는 영향
Abstract
The bile secretion was accelerated generally by the administration of all derivatives tested: chemodeoxycholate, deoxycholate, cholate, dehydrocholate, 7-ketochenodeoxycholate, and 3, 7-diketochenodeoxycholate in decreasing order. Bile acids content in bile from animals administered with cholate was increased, however, other derivatives did not alter the contents of bile acids and bilirubin. In view of pharmacological point, all derivatives have hydrocholeretic action, however, only cholate exhibits typical choleretic action.
Keywords