The Study Concerned with the Hardness of Ointment 1. The Apparent Logarithmic Hardness of Ointment Registered on the Pharmacopeia of Korea

연고제(軟膏劑)의 경도(硬度)에 관(關)한 연구(硏究) 1. 약전수재연고제(藥典收載軟膏劑)의 외견상(外見上)의 대수경도(對數硬度)

  • Published : 1971.11.20

Abstract

The ointment, had discovered and used from the ancient, have not ever defined to qualitity as the hardness concerned with the absorned With the absorption of the effect of durg through the skin. Auther, for the first time, suggest the apparent logarithmic hardness against the penetration of ointment registered on the pharmacopeia of the Republic of Korea, the results are as the followings. 1. The speciality of this apparent logarithmic hardness ie in proportion for the solidity on the contrary to the penetration of oiniment, and the distribution range of it are between 1.68 to 3.53 for their ointments examined. 2. The specific gravity of the verious ointments according to the apparent logarithmic hardness may be ignore on the calculaiotn, the mean valve of the samples was 2.9303. 3. The determination of apparent logarithmic hardness(H) by the penetration method follows the under equation. $H=log_{10}({\frac{P-0.545h^3}{0.855h^2}})$ where, the h is the penetrate length described centimeter, and p is the weight of the cone.

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