2-Substituted Phenyl-5-phenyltetrazole 生成에 있어서의 置換基의 影響에 關하여

Effect of Substituents on the Formation of 2-Substituted Phenyl-5-phenyltetrazole

  • 홍순영 (慶北大學校 文理科大學 化學科)
  • 발행 : 19671200

초록

2-Phenyl-5-substituted phenyltetrazole and 2-substituted phenyl-5-phenyltetrazole were prepared from the corresponding hydrazone and phenyl azide with 2-methoxyethanol and metallic sodium as reaction medium at 110~115 $^{\circ}C$. At this reaction condition, however, the preparation of 2-substituted phenyl-5-phenyltetrazoles with substituents of relatively high Hammett substituent constant was unsuccessful. Surprisingly it was found that the solvent molecule was exchanged with substituent during the reaction when tried to obtain 2-m-fluorophenyl-5-phenyltetrazole using benzaldehyde m-fluorophenylhydrazone as starting material. Also disscussed the effect of electronic nature of substituents on the formation of 2,5-diphenyltetrazole derivatives.

키워드

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