Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 2018.04a
- /
- Pages.67-67
- /
- 2018
Invitro and Virtual Screening of Bioactive Molecule from Mycelium of Trichoderma atroviride Inhibit the UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine Deacetylases (LpxC) for Treatment of Bacterial Infection
- Saravanakumar, Kandasamy (Department of Medical Biotechnology, College of Biomedical Sciences, Kangwon National University) ;
- Park, Cheol-Ho (Department of Medical Biotechnology, College of Biomedical Sciences, Kangwon National University) ;
- Wang, Myeong-Hyeon (Department of Medical Biotechnology, College of Biomedical Sciences, Kangwon National University)
- Published : 2018.04.27
Abstract
Trichoderma species are a rich source of metabolites, but less known for biomedical potential. This work deals with antibacterial and antioxidant potentials of intracellular non-cytotoxic metabolites, extracted from Trichoderma atroviride (KNUP001). A total of 53 fractions was collected by column chromatography and tested for cytotoxicity by MTT assay. Only one fraction (F41) was found to be non-toxic to Vero cells with
Keywords