Proceedings of the Korean Vacuum Society Conference (한국진공학회:학술대회논문집)
- 2013.08a
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- Pages.275-275
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- 2013
Hydrothermal Synthesis of $TiO_2$ Nanowire Array for Osteoblast Adhesion
- Yun, Young-Sik (School of Integrated Technology, Yonsei University) ;
- Kang, Eun-Hye (Department of Plastic & Reconstructive Surgery, College of Medicine, Yonsei University) ;
- Hong, Min-Eui (Seoul Science High School) ;
- Yun, In-Sik (Department of Plastic & Reconstructive Surgery, College of Medicine, Yonsei University) ;
- Kim, Yong-Oock (Department of Plastic & Reconstructive Surgery, College of Medicine, Yonsei University) ;
- Yeo, Jong-Souk (School of Integrated Technology, Yonsei University)
- Published : 2013.08.21
Abstract
Osteoblast is one of cells related with osseointegration and many research have conducted the adhesion of osteoblast onto the surface of implant. In the osseointegration, biocompatibility of the implant and cell adhesion to the surface are important factors. The researches related to cell adhesion have a direction from micro-scaled surface roughness to nano-scaled surface roughness with advancing nanotechnology. A cell reacts and sense to stimuli from extracellular matrix (ECM) and topography of the ECM [1]. Thus, for better osseointegration, we should provide an environment similar to ECM. In this study, we synthesize TiO2 nanowires using hydrothermal reaction because TiO2 provides inertness to titanium on its surface and enables it used as an implant material for the orthopedic treatment such as fixation of the bone fracture [2]. Ti substrate is immersed into NaOH aqueous solution. The solution are heated at