Effects of $N_2/H_2$ plasma treatments on enhancement of neuronal cell affinity on single-walled carbon nanotube paper scaffolds

  • Yoon, Ok-Ja (School of Advanced Materials Science and Engineering, Center for Advanced Plasma Surface Technology and Center for Human Interface Nanotechnology, Sungkyunkwan University) ;
  • Lee, Hyun-Jung (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Jang, Yeong-Mi (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Kim, Hyun-Woo (School of Advanced Materials Science and Engineering, Center for Advanced Plasma Surface Technology and Center for Human Interface Nanotechnology, Sungkyunkwan University) ;
  • Lee, Won-Bok (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Kim, Sung-Su (Department of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Lee, Nae-Eung (School of Advanced Materials Science and Engineering, Center for Advanced Plasma Surface Technology and Center for Human Interface Nanotechnology, Sungkyunkwan University)
  • Published : 2010.02.17

Abstract

The biocompatibility of materials used for biomedical applications depends on chemical composition, mechanical stiffness, surface energy, and roughness. The plasma treatment and etching process is a very important technology in the biomedical fields due to possibility of controlling the surface chemistry and properties of materials. In this work, $N_2/H_2$ plasma were treated on single-walled carbon nanotubes (SWCNTs) paper and characterization of treated SWCNTs paper was carried out. Also we investigated neurite outgrowth from SH-SY5Y on treated SWCNTs paper. The results indicated that $N_2/H_2$ plasma-modified SWCNTs paper enhanced neuronal cell adhesion, viability, neurite outgrowth and branching in vitro and exerted a positive role on the health of neural cells.

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