DNA칩을 이용한 SNP의 검출

SNP Detection Using DNA Chip

  • Choi, Yong-Sung (Department of Electrical Engineering, Dongshin University) ;
  • Moon, Jong-Dae (Department of Electrical Engineering, Dongshin University) ;
  • Lee, Kyung-Sup (Department of Electrical Engineering, Dongshin University)
  • 발행 : 2006.07.12

초록

This research aims to develop the multiple channel electrochemical DNA chip that has the above characteristic and be able to solve the problems. At first, we fabricated a high integration type DNA chip array by lithography technology. It is able to detect a plural genes electrochemically after immobilization of a plural probe DNA and hybridization of non-labeling target DNA on the electrodes simultaneously. It suggested that this DNA chip could recognize the sequence specific genes. It suggested that multichannel electrochemical DNA microarray is useful to develop a portable device for clinical gene diagnostic system.

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