Development of a soft X-ray microscopy system for Biological Application

생물의료용 연 X-선 현미경 시스템 개발

  • 김경우 (원광대학교 익산방사선영상과학연구소) ;
  • 권영만 (원광대학교 익산방사선영상과학연구소) ;
  • 김규겸 (원광대학교 익산방사선영상과학연구소) ;
  • 민종환 (원광대학교 익산방사선영상과학연구소) ;
  • 박정권 (원광대학교 익산방사선영상과학연구소) ;
  • 임종혁 (원광대학교 익산방사선영상과학연구소) ;
  • 남기용 (원광대학교 익산방사선영상과학연구소) ;
  • 윤권하 (원광대학교 의과대학 방사선과) ;
  • 민진영 ((주)리스템)
  • Published : 2005.02.17

Abstract

In this paper the conceptual design and development of a compact vertical type soft x-ray microscope is described. This x-ray microscope operates in the water window wavelength region(2.3 ${\sim}$ 4.4nm), where natural contrast between carbon(protein) and oxygen(water) allows imaging of unstained biological material their natural, hydrated environment. Until now, operational x-ray microscopes are based on synchrotron radiation sources, which limit their accessibility. Many biologists would benefit from having the x-ray microscope as a tool among other tools in their own laboratory, For this purpose we introduced the compact vertical type soft X-ray microscope with 50 nm resolution for biomedical application. The compact vertical type soft x-ray microscope is based on a laser plasma x-ray source, doubled ellipsoidal condenser reflective optics, diffractive zone plate optics and MCP coupled with CCD to record an x-ray image.

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