한국정밀공학회:학술대회논문집 (Proceedings of the Korean Society of Precision Engineering Conference)

한국정밀공학회 (Korean Society for Precision Engineering)
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Long-Term Analysis for the effect of Ovariectomy on Rat Bone using Micro Finite Element Method

  • 고창용 (연세대학교 보건과학대학 의공학과, 의용계측 및 재활공학 연구센터) ;
  • 우대곤 (연세대학교 보건과학대학 의공학과, 의용계측 및 재활공학 연구센터) ;
  • 이태우 (연세대학교 보건과학대학 의공학과, 의용계측 및 재활공학 연구센터) ;
  • 김한성 (연세대학교 보건과학대학 의공학과, 의용계측 및 재활공학 연구센터) ;
  • 이법이 (건국대학교 의과대학 해부학 교실) ;
  • 탁계래 (건국대학교 의료생명대학 의학공학과)
  • Ko C.Y (Department of Biomedical Engineering. College of Health Science, Research Instrumentation and Rehabilitation Engineering, Yonsei University) ;
  • Woo D.G. (Department of Biomedical Engineering. College of Health Science, Research Instrumentation and Rehabilitation Engineering, Yonsei University) ;
  • Lee T.W. (Department of Biomedical Engineering. College of Health Science, Research Instrumentation and Rehabilitation Engineering, Yonsei University) ;
  • Kim H.S. (Department of Biomedical Engineering. College of Health Science, Research Instrumentation and Rehabilitation Engineering, Yonsei University) ;
  • Lee B.Y. (Department of Anatomy. College of Medicine, Kunkuk University) ;
  • Tack G.R. (Department of Biomedical Engineering. College of Medicine, Kunkuk University)
  • 발행 : 2005.10.01
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초록

This study investigated the effect of ovariectomy (OVX) on the rat bone fur long term (22 weeks). In previous researches, there were many studies for morphology of OVX-induced osteoporotic bones based on micro-Computed Tomography (micro-CT). However, there were few studies fpr detecting and tracking changes of mechanical characteristics in the lumbar vertebrae of OVX rat fur long-term. For this study, one female Sprague-Dawley rat was used: an OVX rat. The 4th lumbar of the OVX rat was utilized as a specimen. Morphological characteristics could be investigated fur the lumbar vertebrae in an OVX rat by using in-vivo Micro-CT. An OVX rat was scanned at week 0 (just before surgery), at week 4, at week 8, at week 16 and at week 22 after surgery. Micro finite element $({\mu}FE)$ analysis was used to investigate mechanical characteristics in the lumbar vertebrae for an OVX rat.

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