Proceedings of the KSAR Conference (한국동물번식학회:학술대회논문집)
- 2004.06a
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- Pages.228-228
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- 2004
Differential Expression of Interferon-Tau Transcripts in Bovine Blastocysts Produced by In Vitro Fertilization and Somatic Cell Nuclear Transfer
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Song, Bong-Suk
(Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology)
;
- Koo, Deog-Bon (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnolog) ;
- Gabbine Wee (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnolog) ;
- Shim, Jung-Jae (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnolog) ;
- Kim, Ji-Su (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnolog) ;
- Lee, Kyung-Kwang (Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnolog) ;
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Han, Yong-Mahn
(Laboratory of Development and Differentiation, Korea Research Institute of Bioscience and Biotechnology)
- Published : 2004.06.01
Abstract
Interferon-tau (IFN-τ) is the primary agent responsible for maternal recognition of pregnancy in cattle. Bovine embryos begine to express IFN-τ as the blastocyst forms. Pregnancy recognition in ruminants occurs when IFN-τ from the trophoblast prevents the increase of oxytocin receptors, disrupting luteolytic pulses of prostaglandin (PG) F2a by oxytocin. The expression of IFN-τ is strongly associated with the degree of methylation of the CpG islands in promoter region. (omitted)