Developmental Expression of the Acyl-CoA Synthetase 4 in the Peri-Implantation Mouse Uterus

  • Park, Hyo-Young (Department of Animal Science, College of Agriculture & Life Science, Chonnam National University) ;
  • Lee, Sang-Mi (Department of Animal Science, College of Agriculture & Life Science, Chonnam National University) ;
  • Jeong, Young-Hee (Department of Animal Science, College of Agriculture & Life Science, Chonnam National University) ;
  • Moon, Seung-Ju (Department of Animal Science, College of Agriculture & Life Science, Chonnam National University) ;
  • Kang, Man-Jong (Department of Animal Science, College of Agriculture & Life Science, Chonnam National University)
  • Published : 2004.06.01

Abstract

Acyl-CoA synthetase 4(ACS4) is an arachidonate-preferring enzyme aboundant in steroidogenic tissues and postulated to modulate eicosanoid production. Most of arachidonate present in cells is esterified predominantly in phospholipids. After its release by the action of calcium-dependent phospholipases, arachidonate can be converted to prostaglandins, thromboxanes, and leukotrenes via the cyclooxygenas and lipoxygenase pathways, respectively, depending on the cell type.(omitted)

Keywords