한국동물번식학회:학술대회논문집 (Proceedings of the KSAR Conference)

한국동물번식학회 (The Korean Society of Animal Reproduction)
권호 표지

Biological Function of Single Chain Equine Chorionic Gonadotiopin Mutants(C-terminal Deletions)

  • 정윤희 (한경대학교 생물정보통신전문대학원 동물생명공학과) ;
  • 박종주 (한경대학교 생물정보통신전문대학원 동물생명공학) ;
  • 김민수 (한경대학교 생물정보통신전문대학원 동물생명공학) ;
  • 이유연 (한경대학교 생물정보통신전문대학원 동물생명공학) ;
  • ;
  • 윤종택 (동물생명자원학) ;
  • 민관식 (한경대학교 생물정보통신전문대학원 동물생명공학과)
  • ;
  • ;
  • ;
  • ;
  • N.P JarGil ;
  • ;
  • 발행 : 2004.06.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Equinechorionic gonadotropin(eCG) is a member of the glycoprotein hormone family which includes FSH, hCG, TSH. These hormone family is characterized by a heterodimeric structure composed a common α-subunit noncovalently linked to a hormone specific β-subunit. To determine a and β-subunits can be synthesized as a single polypeptide chain (tethered-eCG) and also display biological activity, the tethered-molecule by fusing the carboxyl terminus of the eCG β-subunit to the amino terminus of the α-subunit was constructed and transfected into chinese hamster ovary (CHO-K1) cells. (omitted)

키워드