Depigmentation activity of plant extracts (Okyong-san)

  • Han, Sung-Chul (Department of Material & Biochemical Engineering Chonnam National University) ;
  • Lee, Young-Jin (Department of Material & Biochemical Engineering, Kwangju Health College & Polymer Engineering, Chonnam National University, Nanobiomed. Inc.) ;
  • Lee, Ki-Young (Faculty of Applied Chemical Engineering Chonnam National University) ;
  • Kim, Yeon-Zu (Chonnam National University, Department of Skin and Beauty) ;
  • Jin, Sang-Hyeop (Kwangju Health College & Polymer Engineering, Chonnam National University, Nanobiomed. Inc.)
  • Published : 2003.10.22

Abstract

The reactive oxygen species (or free radicals) generated by ultraviolet radiation cause damage on cellular components and pigment of skin. The aim of this study was to investigate the skin-whitenig effect of Okyong-san. Inhibitory effects of okyong-san extracts on melanin synthesis were studied. Namely, UV-absorbing ability, free radical scavenging activity and tyrosinase inhibitory activity of okyong-san extracts were investigated. As a result, the extracts of okyong-san were found to inhibit the activity of tyrosinase and they showed an absorbance in the UV-B region and UV-C region. We also observed that extracts of okyong-san had free radical scavenging activity.

천연추출물로서 미백 재료로 널리 쓰이고 있는 옥용산에 대해서 in vitro 미백활성을 UV 흡수능, tyrosinase 저해활성 그리고 free radical 소거활성을 측정함으로서 검정해 보았다. 옥용산 UV-B와 C 영역에 걸쳐서 높은 자외선 흡수능을 보이는 것으로 관찰이 되었으며 0.8 % 이상의 농도에서 80% 이상의 tyrosinase 저해활성을 가지는 것을 관찰하였다. 또한 조협, 승마, 감송, 정향, 찹쌀분과 옥용산의 추출물은 높은 free radical 소거능을 가지는 것으로 확인되었다.

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