Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.246.1-246.1
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- 2003
Bioequivalence of Two Enalapril Maleate Tablets (Enalapril maleate 20 mg)
- Lee, Sun-Young (iBiopharm Co., Ltd. Research Laboratory) ;
- Kim, Dong-Chool (College of Pharmacy, Chungnam National University)
- Published : 2003.10.01
Abstract
Bioequivalence of two enalapril maleate tablets, formulation A and B, was evaluated according to the Korean Guidelines for Bioequivalence Test (KGBT 2001). Twenty healthy male volunteers (19∼27 years old) were randomly divided into two groups and a randomized 2x2 cross-over study was performed. Following oral administration of enalapril maleate tablets (20 mg dose), blood sample was taken at pre-determined time intervals and the concentrations of enalapril in plasma were determined using LC-MS. (omitted)
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