Cytotoxic Activity of Styrax japonica S. et Z.

  • Kim, Mi-Ran (Research Center for Proteineous Materials, Chosun University) ;
  • Lee, Hyang-Hee (Research Center for Proteineous Materials, Chosun University) ;
  • Hahm, Kyung-Soo (Research Center for Proteineous Materials, Chosun University) ;
  • Woo, Eun-Rhan (Research Center for Proteineous Materials, Chosun University/College of Pharmacy, Chosun University)
  • Published : 2003.10.01

Abstract

The genus Styrax (Styracaceae) is different from other genera of this family due to the production of resinous material, usually secreted when the barks and trunks are injured by sharp objects. This resin, in the past considered a miraculous remedy in several parts of Asia and America, has been used in traditional medicine to treat inflammatory diseases. The CH$_2$Cl$_2$ fraction of Styrax japonica showed significant cytotoxic activities by SRB method against five human tumor cell lines (A549, HCT-15, MES-SA, SK-OV-3, and SK-MEL-2). (omitted)

Keywords