Quantitative analysis of 5-hydroxymethyl-2-furaldehyde (5-HMF) in the commercial Rehmanniae Radix Preparata

  • Kim, Ho-Kyoung (Korea Institute of Oriental Medicine, Quality control of Herbal Medicine Department) ;
  • Jeon, Won-Kyung (Korea Institute of Oriental Medicine, Quality control of Herbal Medicine Departmen) ;
  • Kim, Young-A (Korea Institute of Oriental Medicine, Quality control of Herbal Medicine Departmen) ;
  • Ko, Byung-Seob (Korea Institute of Oriental Medicine, Quality control of Herbal Medicine Department)
  • Published : 2003.10.01

Abstract

Rehmanniae Radix Preparata attributes good blood circulation and it has been used for the treatment of dizziness, men's sterility, excessive loss of blood and weakness. On the quality control of the commercial Rehmanniae Radix Preparata, quantitative determination of 5-hydroxymethyl-2-furaldehyde (5-HMF) using HPLC method has been conducted. Quantitative analysis of 5-HMF in Rehmanniae Radix Preparata showered average 0.121${\pm}$0.063% in 14 samples collected throughout the regions of Korea. Contents of loss on drying, residue on ignition and residue on acid insoluble ignition showered average 14.084${\pm}$2.804%, 3.415${\pm}$0.790% and 0.807${\pm}$0.474% respectively.

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