Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.168.1-168.1
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- 2003
Panaxadiol Arrests Cell Cycle by Elevating $p21^{WAF1/CIP1}$
- Choi, Joon-Seok (College of pharmacy, Seoul National University) ;
- Jin, Ying-Hua (College of Medicine, Chungbuk National University) ;
- Shin, Soon-A (College of Medicine, Chungbuk National University) ;
- Lee, Kwang-Yeol (College of Medicine, Chungbuk National University) ;
- Park, Jeong-Hill (College of Medicine, Chungbuk National University) ;
- Lee, Seung-Ki (College of Medicine, Chungbuk National University)
- Published : 2003.10.01
Abstract
We show that panaxadiol (PD), a ginseng saponin with a dammarane skeleton, selectively interferes with the cell cycle in human cancer cell lines. PD inhibited DNA synthesis in a dose-dependent manner with
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